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SDS

COO/COA

OCY311
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Cyanine3 Trans-Cyclooctene
suitable for HPLC, ≥95%
Synonym(s): Cy3-TCO
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Pack Size SKU Availability Price Quantity
1mg OCY311-1mg In stock $209.00
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5mg OCY311-5mg In stock $439.00
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10mg OCY311-10mg In stock $597.00
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25mg OCY311-25mg In stock $955.00
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50mg OCY311-50mg In stock $1489.00
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Product Information
General Properties
Other Properties
Description
Safety Information
Product Information
CAS Number
Linear Formula

C41H55ClN4O3

Molecular weight 687.37
Beilstein
EC Number

MDL Number

PubChem CID
General Properties
Purity 95%
Appearance Red powder
Solubility Freely soluble in methanol, chloroform, DMSO, and DMF; poorly soluble in water.
Purity Testing Method HPLC
Structural Identification Method NMR/MS
Storage Conditions −20 °C, keep in dark place.
Other Properties
DESCRIPTION

Cyanine3 Trans-Cyclooctene is a bioorthogonal reagent engineered for rapid, copper-free click chemistry with tetrazine derivatives via inverse electron-demand Diels-Alder (IEDDA) reactions. This non-sulfonated Cy3 conjugate features a strained trans-cyclooctene (TCO) group that achieves exceptional reaction kinetics (k₂ ~10³–10⁴ M⁻¹s⁻¹), enabling ultra-fast labeling in live-cell imaging, in vivo tracking, and time-sensitive diagnostic applications.
Key Features:
• Rapid Tetrazine Ligation: Completes within minutes at µM concentrations
• Minimal Background: Superior to linear alkene counterparts
• Dual Functionality: Combines Cy3 fluorescence with bioorthogonal reactivity

SAFETY INFORMATION
  • Symbol GHS

  • Hazard Code

  • Risk Statements

  • Safety Statements

  • RIDADR

  • WGK Germany

  • RTECS

  • F

  • Hazard Class

  • Packing Group

  • HS Code

  • Toxicity

  • Autoignition Temperature

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REFERENCES
1. Highly sensitive reduced graphene oxide impedance sensor harnessing π-stacking interaction mediated direct deposition of protein probes.
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