Cyanine3 NHS ester | 95% | CAS NO. 1032678-38-8

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SDS

COO/COA

OCY302

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Cyanine3 NHS ester

suitable for HPLC, ≥95%

Synonym(s): Cy3-NHS

Select a Size

Pack Size	SKU	Availability	Price	Quantity
1mg	OCY302-1mg	In stock	$81.00	- +
5mg	OCY302-5mg	In stock	$107.00	- +
10mg	OCY302-10mg	In stock	$182.00	- +
25mg	OCY302-25mg	In stock	$459.00	- +
50mg	OCY302-50mg	In stock	$805.00	- +

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Product Information

General Properties

Other Properties

Description

Safety Information

Product Information

CAS Number	1032678-38-8
Linear Formula	C₃₄H₄₀ClN₃O₄
Molecular weight	590.16
Beilstein
EC Number
MDL Number
PubChem CID	121226457
PubChem SID	517723047

General Properties

Purity	95%
Appearance	Red powder
Solubility	Freely soluble in methanol, chloroform, DMSO, DMF, and other organic solvents; insoluble in water.
Purity Testing Method	HPLC
Structural Identification Method	NMR/MS
Storage Conditions	−20 °C, keep in dark place.

Other Properties

Spectral Properties

Excitation Wavelength (λₑₓ)	555 nm
Emission Wavelength (λₑₘ)	570 nm
Molar Extinction Coefficient (ε)	149000 L·mol⁻¹·cm⁻¹

DESCRIPTION

Cyanine3 NHS ester is a reactive dye for efficient amine conjugation, forming stable amide bonds with proteins, peptides, and other biomolecules. This non-sulfonated reagent offers excellent organic solubility and high labeling efficiency. The NHS ester group ensures rapid, selective reactions with primary amines at pH 7-9. Ideal for fluorescence labeling in bioimaging, immunoassays, and molecular probes.
For aqueous applications, consider sulfo-Cyanine3 NHS ester, which provides enhanced water solubility. Store desiccated at -20°C, protected from light and moisture.

SAFETY INFORMATION

Symbol GHS
Hazard Code
Risk Statements
Safety Statements
RIDADR
WGK Germany
RTECS
F
Hazard Class
Packing Group
HS Code
Toxicity
Autoignition Temperature

1. Yang, J.; Zhang, R.; Radford, D.C.; Kope?ek, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045

2. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c

3. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972

4. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008

5. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176

6. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d

7. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kope?ek, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005

8. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028

9. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036

10. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014

Key Documents

OCY302

Symbol GHS

Hazard Code

Risk Statements

Safety Statements

RIDADR

WGK Germany

RTECS

F

Hazard Class

Packing Group

HS Code

Toxicity

Autoignition Temperature

1. Yang, J.; Zhang, R.; Radford, D.C.; Kope?ek, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045

2. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c

3. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972

4. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008

5. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176

6. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d

7. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kope?ek, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005

8. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028

9. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036

10. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014

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Key Documents

OCY302

Symbol GHS

Hazard Code

Risk Statements

Safety Statements

RIDADR

WGK Germany

RTECS

F

Hazard Class

Packing Group

HS Code

Toxicity

Autoignition Temperature

OCY311

Cyanine3 Trans-Cyclooctene

OCY310

Cyanine3 SH

OCY309

Cyanine3 amine

OCY308

Cyanine3 Biotin

OCY307

Cyanine3 DBCO

OCY306

Cyanine3 alkyne

OCY305

Cyanine3 azide

OCY304

Cyanine3 tetrazine

OCY303

Cyanine3 maleimide

OCY301

Cyanine3 carboxylic acid

1. Yang, J.; Zhang, R.; Radford, D.C.; Kope?ek, J. FRET-trackable biodegradable HPMA copolymer-epirubicin conjugates for ovarian carcinoma therapy. Journal of Controlled Release, 2015, 218, 36–44. doi: 10.1016/j.jconrel.2015.09.045

2. Albertazzi, L.; van der Veeken, N.; Baker, M.B.; Palmans, A.R.A.; Meijer, E.W. Supramolecular copolymers with stimuli-responsive sequence control. Chemical Communications, 2015, 51(90), 16166–16168. doi: 10.1039/c5cc06951c

3. Koo, H.; Choi, M.; Kim, E.; Hahn, S.K.; Weissleder, R.; Yun, S.H. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small, 2015, 11(48), 6458–6466. doi: 10.1002/smll.201502972

4. Poongavanam, M.-V.; Kisley, L.; Kourentzi, K.; Landes, C.F.; Willson, C. Ensemble and Single-Molecule Biophysical Characterization of D17.4 DNA Aptamer-IgE Interactions. Biochimica et Biophysica Acta, 2016, 1864(1), 154–164. doi: 10.1016/j.bbapap.2015.08.008

5. Kijima, S.T.; Hirose, K.; Kong, S.-G.; Wada, M.; Uyeda, T.Q.P. Distinct Biochemical Properties of Arabidopsis thaliana Actin Isoforms. Plant and Cell Physiology, 2016, 57(1), 46–56. doi: 10.1093/pcp/pcv176

6. Leenders, J.; Baker, M.B.; Pijpers, I.; Lafleur, R.; Albertazzi, L.; Palmans, A.R.A.; Meijer, E.W. Supramolecular polymerisation in water; elucidating the role of hydrophobic and hydrogen-bond interactions. Soft Matter, 2016, 12, 2887–2893. doi: 10.1039/c5sm02843d

7. Hartley, J.M.; Zhang, R.; Gudheti, M.; Yang, J.; Kope?ek, J. Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM. Journal of Controlled Release, 2016, 231, 50–59. doi: 10.1016/j.jconrel.2016.02.005

8. Ray, J.; Shin, I.; Ilgu, M.; Bendickson, L.; Gupta, V.; Kraus, G.A.; Nilsen-Hamilton, M. IMAGEtags: Quantifying mRNA Transcription in Real Time with Multiaptamer Reporters. Methods in Enzymology, 2016, 572, 193–213. doi: 10.1016/bs.mie.2016.02.028

9. Zhong, Q.; Merkel, O.M.; Reineke, J.J.; da Rocha, S.R.P. Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on their Systemic and Lung Cellular Biodistribution. Molecular Pharmaceutics, 2016, 13(6), 1866–1878. doi: 10.1021/acs.molpharmaceut.6b00036

10. Wang, C.; Tang, F.; Wang, X.; Li, L. Synthesis and application of biocompatible gold core-poly-(L-Lysine) shell nanoparticles. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 506, 425–430. doi: 10.1016/j.colsurfa.2016.07.014

omichem

SIGN UP & SAVE 10%

Applies to full-price items only. Online exclusive.

By submitting your email, you agree to:

Receive promotional emails from OMICHEM (unsubscribe anytime)

Our Terms of Use (including arbitration clause)

Data sharing with service providers as per our Privacy Policy